Chemo-centric

Product Name Product Description Specification
SL#006 Glycomimetics (Piperidines)
Release: 04/24/2016

Carbohydrates are fundamental components of every cell surface, where they are involved in vital cellular recognition processes.

In library: Glycomimetics
SL#007 Glycomimetics (Pyrrolidine)
Release: 04/25/2016

Carbohydrates are fundamental components of every cell surface, where they are involved in vital cellular recognition processes.

In library: Glycomimetics
SL#008 Glycomimetic Macrocycles-1
Release: 04/26/2016

Carbohydrates are the most abundant natural products. They participate in metabolism and serve as structural building blocks. Carbohydrates are fundamental constituents of every cell surface, where they are involved in vital cellular recognition processes.

In library: MACRO Glycomimetics
SL#010 Purine-based Nucleosides
Release: 04/29/2016

The enzyme co-factor SAM/SAH is found in all branches of life, widely exploited by protein methyltransferases for the transfer of a methyl group to various molecules of biological significance. A number of these enzymes are drug targets in the field of epigenetics [1].     

In library: Purine Nucleosides
SL#016 Glycomimetic Macrocycles-2
Release: 05/29/2016

Carbohydrates are fundamental constituents of every cell surface, where they are involved in vital cellular recognition processes. Glycomimetics are designed to mimic the structure of natural carbohydrates and modulate their disease-related function.

In library: MACRO Glycomimetics
SL#017 Aza Glycomimetics
Release: 05/14/2016

Polyhydroxylated secondary and tertiary amines are found among several interesting natural products having a wide range of biological activities due to their glycomimtic properties [1].

In library: Glycomimetics
SL#018 Spiro Peptidomimetics
Release: 05/17/2016

A variety of non-peptide small molecules that can mimic the structure or biological function of peptides have found application in drug discovery.

In library: Peptidomimetic
SL#019 Soft Electrophiles-1 Covalent Inhibitors
Release: 05/21/2016

In screening library creation, reactive molecules have been disregarded due to selectivity and safety concerns. However, many successful drugs act as covalent inhibitors based on a specific reactive group or moiety [1].

In library: Soft Electrophiles
SL#020 Soft Electrophiles-2 Covalent Inhibitors
Release: 05/21/2016

In screening library creation, reactive molecules have been disregarded due to selectivity and safety concerns. However, many successful drugs act as covalent inhibitors based on a specific reactive group or moiety [1].

In library: Soft Electrophiles
SL#022 Soft Electrophiles-3. Covalent Inhibitors
Release: 06/05/2016

In screening library creation, reactive molecules have been disregarded due to selectivity and safety concerns. However, many successful drugs act as covalent inhibitors due to the presence of a specific reactive group or moiety [1].

In library: Soft Electrophiles
SL#027 Soft Electrophiles-4. Covalent Inhibitors
Release: 06/25/2016

Historically, in screening libraries, reactive molecules have been disregarded due to selectivity and safety concerns. However, many successful drugs act as covalent inhibitors based on a specific reactive group or moiety [1].

In library: Soft Electrophiles
SL#028 Glycomimetics (Pyrrolidine)
Release: 04/06/2016

Carbohydrates are fundamental components of every cell surface where they are involved in vital cellular recognition processes. Despite their physiological importance they are rarely used as drugs due to their poor pharmacodynamic and pharmacokinetic properties.

In library: Glycomimetics
SL#036 Glycomimetic Macrocycles-3
Release: 07/27/2016

Glyco-macrocycles are an extremely interesting class of glycomimetics as they occupy space between small and macro molecules. Glyco-macrocycles are mostly represented by naturally occurring molecules derived from marine microorganisms and bacterial or fungal metabolites.

In library: MACRO Glycomimetics
SL#037 Soft Electrophiles CN
Release: 08/19/2016

Covalent inhibitors often possess an electrophilic “warhead” which interacts with a nucleophilic residue at the binding site under certain physiological conditions; examples of such electrophilic groups include acrylamides, epoxides, nitriles, and electron-deficient ketones.  

In library: Soft Electrophiles
SL#038 Immuno Glycomimetics
Release: 07/18/2016

Oligosaccharides are key components in the antigen-antibody and host-pathogen recognition process. Despite the physiological importance of carbohydrates they are rarely used as drugs because of their poor pharmacodynamic and pharmacokinetic properties.

In library: Glycomimetics
SL#039 Glycomacrocycles-4
Release: 07/21/2016

Glycomacrocycles are an extremely interesting class of glycomimetics that occupy space between small and macro molecules. Glycomacrocycles are mostly represented by naturally occurring molecules derived from marine microorganisms and bacterial or fungal metabolites.

In library: MACRO Glycomimetics
SL#040 Constrained tetrapeptides
Release: 07/25/2016

Therapeutic application of peptides has recently expanded to HIV, osteoporosis, cancer, and CNS-related disease.

In library: Peptidomimetic